TargetMol

Nepetoidin B

Product Code:
 
TAR-TN4648
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN4648-1mg1mg£239.00
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Further Information

Bioactivity:
Nepetoidin B has anti-fungal, anti-bacterial, and antiinflammatory effects, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated by MKP-5/NF-κB pathways in RAW 264.7 cells.
CAS:
55486-06-1
Formula:
C17H14O6
Molecular Weight:
314.29
Pathway:
Apoptosis; Microbiology/Virology; Neuroscience; MAPK; NF-κb; Immunology/Inflammation
Purity:
0.98
SMILES:
Oc1ccc(C=C/OC(=O)C=Cc2ccc(O)c(O)c2)cc1O
Target:
IL Receptor; p38 MAPK; TNF; NOS; NF-κB; COX; JNK; Antifection

References

Falcao RA, et al. Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evid Based Complement Alternat Med. 2013;2013:460613. Wu X, et al. Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-?B/MKP-5 Pathways. Phytother Res. 2017;31(7):1072-1077.