TargetMol

Siegeskaurolic acid

Product Code:
 
TAR-TN5019
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TN5019-1mg1mg£593.00
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Further Information

Bioactivity:
Siegeskaurolic acid exhibits anti-inflammatory and antinociceptive effects, which due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation.
CAS:
52645-97-3
Formula:
C20H32O3
Molecular Weight:
320.47
Pathway:
Neuroscience; GPCR/G Protein; NF-κb; Immunology/Inflammation; Apoptosis
Purity:
0.98
SMILES:
C[C@@]12CCC[C@](C)([C@H]1CC[C@@]13C[C@@H](CO)[C@@H](C1)CC[C@@H]23)C(O)=O
Target:
TNF; NOS; NF-κB; COX; Prostaglandin Receptor

References

Park HJ, et al. Anti-inflammatory activities of ent-16alphaH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation. Eur J Pharmacol. 2007 Mar 8;558(1-3):185-93.