Tectol
Code | Size | Price |
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TAR-TN6512-1mg | 1mg | £158.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN6512-5mg | 5mg | £286.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN6512-1mL | 1 mL * 10 mM (in DMSO) | £309.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN6512-10mg | 10mg | £389.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN6512-25mg | 25mg | £603.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44?0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
CAS:
24449-39-6
Formula:
C30H26O4
Molecular Weight:
450.52
Pathway:
Microbiology/Virology; Metabolism
Purity:
0.9923
SMILES:
CC(C)(C=C1)Oc(c2ccccc22)c1c(-c(c1c(c3ccccc33)OC(C)(C)C=C1)c3O)c2O
Target:
Transferase; Parasite
References
Costa SM, et al. Chemical constituents from Lippia sidoides and cytotoxic activity. J Nat Prod. 2001 Jun;64(6):792-5.
Cadelis MM, et al. Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors. Bioorg Med Chem. 2016;24(14):3102-3107.