5-Hydroxy-2?,3,4?,7-tetramethoxyflavone
Code | Size | Price |
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TAR-TN7124-1mg | 1mg | £227.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7124-2mg | 2mg | £306.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7124-5mg | 5mg | £430.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7124-10mg | 10mg | £613.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7124-25mg | 25mg | £997.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN7124-50mg | 50mg | £1,458.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
5-Hydroxy-2?,3,4?,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 ?M in the Hoechst 33342 and pheophorbide A assays.
CAS:
19056-75-8
Formula:
C19H18O7
Molecular Weight:
358.34
Pathway:
Membrane transporter/Ion channel
Purity:
0.985
SMILES:
O=C1C(OC)=C(OC=2C=C(OC)C=C(O)C12)C=3C=CC(OC)=CC3OC
Target:
ABC
References
You Q, et al. Pharmacokinetics and Metabolites of 12 Bioactive Polymethoxyflavones in Rat Plasma. J Agric Food Chem. 2021 Nov 3;69(43):12705-12716.
Gallus J, Juvale K, Wiese M. Characterization of 3-methoxy flavones for their interaction with ABCG2 as suggested by ATPase activity. Biochim Biophys Acta. 2014 Nov;1838(11):2929-38.