TargetMol

CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)

Product Code:
 
TAR-TP1501L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1501L-1mg1mg£176.00
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Quantity:
TAR-TP1501L-5mg5mg£318.00
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TAR-TP1501L-10mg10mg£542.00
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TAR-TP1501L-25mg25mg£824.00
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Quantity:
TAR-TP1501L-50mg50mg£1,099.00
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Quantity:
TAR-TP1501L-100mg100mg£1,452.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
CAS:
TP1501L
Formula:
C54H75N13O16S2
Molecular Weight:
1226.39
Pathway:
Proteases/Proteasome
Purity:
0.9971
SMILES:
C[C@@H](O)[C@H]1C(N[C@@H]([C@H](O)C)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CNC4=CC=CC=C43)C(NCC(N[C@@H](CC5=CC=CC=C5)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CSSC[C@H](N)C(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
Target:
MMP

References

Medina OP, et al. Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro. Cancer Res. 2001 May 15;61(10):3978-85.