HSDVHK-NH2

TargetMol
Product Code: TAR-TP1879
Supplier: TargetMol
CodeSizePrice
TAR-TP1879-1mg1mg£128.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
CAS:
848644-86-0
Formula:
C30H48N12O9
Molecular Weight:
720.78
Purity:
0.98
SMILES:
0

References

Choi et al (2010) Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics 10 72 PMID: Lee et al (2004) High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J.Biomol.Screen. 9 687 PMID: Bang et al (2011) Pharmacoproteomic analysis of a novel cell-permeable inhibitor of tumor-induced angiogenesis. Mol.Cell Proteomics 10 M110 PMID: