tcY-NH2

TargetMol
Product Code: TAR-TP1925
Supplier: TargetMol
CodeSizePrice
TAR-TP1925-1mg1mg£246.00
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Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
CAS:
327177-34-4
Formula:
C40H49N7O7
Molecular Weight:
739.87
Purity:
0.98
SMILES:
0

References

Ma et al (2001) Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br.J.Pharmacol. 134 701 PMID: Hollenberg and Saifeddine (2001) Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet aggregation by PAR4-derived peptides. Can.J.Physiol.Pharmacol. 79 439 PMID: Hollenberg et al (2004) Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br.J.Pharmacol. 143 443 PMID: