P110 TFA

TargetMol
Product Code: TAR-TP1947L
Supplier: TargetMol
CodeSizePrice
TAR-TP1947L-1mg1mg£99.00
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Quantity:
TAR-TP1947L-5mg5mg£133.00
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Quantity:
TAR-TP1947L-10mg10mg£168.00
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Quantity:
TAR-TP1947L-25mg25mg£262.00
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Quantity:
TAR-TP1947L-50mg50mg£359.00
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Quantity:
TAR-TP1947L-100mg100mg£505.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity.
CAS:
TP1947L
Formula:
C102H180F3N45O27
Molecular Weight:
2525.8
Purity:
1
SMILES:
[H]N[C@@H](CC1=CC=C(O)C=C1)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCC(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N2CCC[C@H]2C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F

References

Filichia et al (2016) Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Sci.Rep. 13 32656 PMID: Qi et al (2013) A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. J.Cell Sci. 126 789 PMID: