PKI(5-24)
| Code | Size | Price |
|---|
| TAR-TP1957-1mg | 1mg | £163.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
High affinity PKA inhibitor (Ki = 2.3 nM).
CAS:
99534-03-9
Formula:
C76H129N31O28
Molecular Weight:
1925.057
Purity:
0.98
SMILES:
CCCC(NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)C(NC(=O)CC(C)O)C(C)O)C(=O)NC(C)C(=O)NC(CO)C(=O)NCC(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(O)=O)C(O)=O
References
Narayana et al (1997) Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine. Biochemistry 36 4438 PMID:
Cheng et al (1986) A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J.Biol.Chem. 261 989 PMID: