Pseudo RACK1
| Code | Size | Price |
|---|
| TAR-TP1971-1mg | 1mg | £340.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37?C, ensuring rapid and effective uptake of the activator peptide. Once inside the cell, the disulfide bonds are subjected to reduction in the cytoplasm leading to release of the activator peptide.
CAS:
TP1971
Formula:
C144H225N43O34S3
Molecular Weight:
3198.81
Purity:
0.98
SMILES:
0
References
Theodore et al (1995) Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J.Neurosci. 15 7158 PMID:
Derossi et al (1994) The third helix of the antennapedia homeodomain translocates through biological membranes. J.Biol.Chem. 269 10444 PMID:
Ron and Mochly-Rosen (1995) An autoregulatory region in protein kinase C: the pseudoanchoring site. Proc.Natl.Acad.Sci.U.S.A. 92 492 PMID: