[Ala11,D-Leu15]-Orexin B acetate

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TargetMol
Product Code: TAR-TP1975L
Supplier: TargetMol
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TAR-TP1975L-1mg1mg£491.00
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TAR-TP1975L-5mg5mg£1,017.00
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TAR-TP1975L-10mg10mg£1,491.00
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TAR-TP1975L-25mg25mg£2,628.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Further Information

Bioactivity:
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).
CAS:
0
Formula:
C122H210N44O37S
Molecular Weight:
2917.31
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.98
SMILES:
CC(O)=O.CSCC[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](C)NC([C@H](CC1=CNC=N1)NC([C@H](CC(N)=O)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H]2N(C([C@H]3N(C(CNC([C@H](CO)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)CCC3)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Target:
OX Receptor

References

Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113.