Kisspeptin-54(human)
| Code | Size | Price |
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| TAR-TP2005-1mg | 1mg | £777.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Potent endogenous ligand of the kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.80 and 1.45 nM respectively. Inhibits chemotaxis, invasion and metastasis of human melanomas and breast carcinomas. Stimulates gonadotropin secretion following i.c.v. administration.
CAS:
374683-24-6
Formula:
C258H401N79O78
Molecular Weight:
5857.49
Purity:
0.98
SMILES:
0
References
Gottsch et al (2004) A role for kisspeptins in the regulation of g.tropin secretion in the mouse. Endocrinology 145 4073 PMID:
Kotani et al (2001) The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J.Biol.Chem. 276 34631 PMID:
Ohtaki et al (2001) Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 411 613 PMID: