GRP (porcine)
| Code | Size | Price |
|---|
| TAR-TP2026-1mg | 1mg | £273.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA release and fear suppression in mice in vivo. Also involved in mitogenesis, and GI tract and appetite regulation.
CAS:
74815-57-9
Formula:
C126H198N38O31S2
Molecular Weight:
2805.31
Purity:
0.98
SMILES:
0
References
Schjoldager et al (1991) Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction. Am.J.Physiol. 260 G577 PMID:
Shumyatsky et al (2002) Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell 111 905 PMID:
Dudai (2003) Neurobiology: Fear thou not. Nature 421 325 PMID:
Woodruff et al (1996) Bombesin receptors in the brain. Ann.N.Y.Acad.Sci. 780 223 PMID: