Calcineurin Autoinhibitory Peptide
| Code | Size | Price |
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| TAR-TP2054-1mg | 1mg | £210.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).
CAS:
148067-21-4
Formula:
C124H205N39O39S2
Molecular Weight:
2930.34
Purity:
0.98
SMILES:
0
References
Hashimoto et al (1990) Identification of an autoinhibitory domain in calcineurin. J.Biol.Chem. 265 1924 PMID:
Yokoyama and Wang (1994) The role of the autoinhibitory domain in differential metal ion activation of calmodulin-stimulated phosphatase. FEBS Lett. 337 128 PMID:
Perrino et al (1995) Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. J.Biol.Chem. 270 340 PMID: