TAT 14

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TargetMol
Product Code: TAR-TP2109
Supplier: TargetMol
CodeSizePrice
TAR-TP2109-1mg1mg£189.00
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TAR-TP2109-5mg5mg£437.00
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TAR-TP2109-10mg10mg£655.00
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Quantity:
TAR-TP2109-25mg25mg£1,075.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TAT 14, a 14-mer peptide, is an Nrf2 activator with anti-inflammatory properties. TAT-14 increases Nrf2 protein levels due to targeting the Nrf2 binding site on Keap1, but has no effect on Nrf2 mRNA expression.
CAS:
1362661-34-4
Formula:
C137H230N48O39
Molecular Weight:
3173.59
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
CC[C@H](C)[C@@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)NC([C@H](CCC1)N1C([C@H](CC(C)C)NC([C@H](Cc1ccccc1)NC([C@H](CCC(O)=O)NC(CNC([C@H]([C@@H](C)O)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](Cc(cc1)ccc1O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Target:
Nrf2

References

Steel et al (2012) Anti-inflammatory effect of a cell-penetrating peptide targeting the Nrf2/Keap1 interaction. ACS Med.Chem.Lett. 3 407 PMID: