MT-DADMe-ImmA

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TargetMol
Product Code: TAR-TQ0008
Supplier: TargetMol
CodeSizePrice
TAR-TQ0008-1mg1mg£122.00
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TAR-TQ0008-5mg5mg£181.00
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TAR-TQ0008-1mL1 mL * 10 mM (in DMSO)£209.00
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TAR-TQ0008-10mg10mg£261.00
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TAR-TQ0008-25mg25mg£430.00
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TAR-TQ0008-50mg50mg£600.00
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TAR-TQ0008-100mg100mg£825.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).
CAS:
653592-04-2
Formula:
C13H19N5OS
Molecular Weight:
293.39
Purity:
0.9953
SMILES:
CSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O

References

Basu I, et al. A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers. J Biol Chem. 2007 Jul 20;282(29):21477-86. Evans GB, et al. Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase. J Med Chem. 2005 Jul 14;48(14):4679-89.