TargetMol

DG051

Product Code:
 
TAR-TQ0047
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-TQ0047-1mg1mg£164.00
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TAR-TQ0047-1mL1 mL * 10 mM (in DMSO)£430.00
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TAR-TQ0047-5mg5mg£448.00
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TAR-TQ0047-10mg10mg£619.00
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TAR-TQ0047-25mg25mg£863.00
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TAR-TQ0047-50mg50mg£1,187.00
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TAR-TQ0047-100mg100mg£1,581.00
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This product comes from: United States.
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Further Information

Bioactivity:
DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50: 47 nM).
CAS:
929915-58-2
Formula:
C22H28ClNO4
Molecular Weight:
405.92
Pathway:
Metabolism
Purity:
0.9812
SMILES:
Cl.Cc1ccc(Oc2ccc(OC[C@@H]3CCCN3CCCC(O)=O)cc2)cc1
Target:
Aminopeptidase

References

Sandanayaka V, et al. Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis. J Med Chem. 2010 Jan 28;53(2):573-85. Enache LA, et al. Synthesis and structural assignment of two major metabolites of the LTA4H inhibitor DG-051. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6275-9.