Fadraciclib

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TargetMol

Product Code: TAR-TQ0053

Product Group: Inhibitors and Activators

Supplier: TargetMol

Code	Size	Price

TAR-TQ0053-1mg

1mg

£125.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-TQ0053-5mg

5mg

£209.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-TQ0053-1mL

1 mL * 10 mM (in DMSO)

£222.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-TQ0053-10mg

10mg

£322.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-TQ0053-25mg

25mg

£499.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-TQ0053-50mg

50mg

£687.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-TQ0053-100mg

100mg

£938.00

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Shipping:

cool pack

Storage:

-20℃

Images

1 / 1

Documents

Further Information

Bioactivity:

Fadraciclib is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).

CAS:

1070790-89-4

Formula:

C21H31N7O

Molecular Weight:

397.527

Pathway:

Cell Cycle/Checkpoint

Purity:

0.9871

SMILES:

CC[C@H](Nc1nc(NCc2cnc(C)cc2C)c2ncn(C(C)C)c2n1)[C@@H](C)O

Target:

CDK

References

Cocco E, et al. Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo. Br J Cancer. 2016 Jul 26;115(3):303-11. Sumana Devata, et al. Molecular markers and venous thromboembolism (VTE) in acute myelogenous leukemia (AML)