CK2/ERK8-IN-1
Code | Size | Price |
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TAR-T10827-5mg | 5mg | £104.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T10827-1mL | 1 mL * 10 mM (in DMSO) | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T10827-10mg | 10mg | £124.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CK2/ERK8-IN-1 is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 ?M) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 ?M, 11.9 ?M, and 15.25 ?M).
CAS:
1085822-09-8
Formula:
C11H9Br4N3O2
Molecular Weight:
534.82
Pathway:
Stem Cells; Apoptosis; Chromatin/Epigenetic; MAPK; JAK/STAT signaling; Tyrosine Kinase/Adaptors; Metabolism; Cell Cycle/Checkpoint
Purity:
0.9802
SMILES:
O=C(O)CN1C=2C(Br)=C(Br)C(Br)=C(Br)C2N=C1N(C)C
Target:
Apoptosis; ERK; Casein Kinase; Pim; DYRK
References
1. Pagano MA, et al. The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 2008 Nov 1;415(3):353-65.