IBR2

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TargetMol
Product Code: TAR-T11600
Supplier: TargetMol
CodeSizePrice
TAR-T11600-2mg2mg£102.00
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TAR-T11600-5mg5mg£122.00
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TAR-T11600-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T11600-10mg10mg£161.00
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Quantity:
TAR-T11600-25mg25mg£253.00
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Quantity:
TAR-T11600-50mg50mg£414.00
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TAR-T11600-100mg100mg£584.00
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TAR-T11600-500mg500mg£1,171.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
IBR2 is a potent and specific RAD51 inhibitor that inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth, and induces apoptosis.
CAS:
313526-24-8
Formula:
C24H20N2O2S
Molecular Weight:
400.5
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9615
SMILES:
O=S(=O)(Cc1ccccc1)N1C=Cc2ccccc2C1c1c[nH]c2ccccc12
Target:
DNA/RNA Synthesis

References

1. Zhu J, et al. Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. Eur J Med Chem. 2015;96:196-208.