IRAK4-IN-4

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TargetMol
Product Code: TAR-T11673
Supplier: TargetMol
CodeSizePrice
TAR-T11673-1mg1mg£174.00
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TAR-T11673-2mg2mg£222.00
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TAR-T11673-5mg5mg£304.00
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TAR-T11673-1mL1 mL * 10 mM (in DMSO)£330.00
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TAR-T11673-10mg10mg£438.00
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TAR-T11673-25mg25mg£675.00
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TAR-T11673-50mg50mg£922.00
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TAR-T11673-100mg100mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor?associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
CAS:
1850276-58-2
Formula:
C22H16N2O2
Molecular Weight:
340.382
Pathway:
Immunology/Inflammation; NF-κb
Purity:
0.9913
SMILES:
Cc1ccn2c(C(=O)C(=O)c3ccccc3)c(nc2c1)-c1ccccc1
Target:
IRAK; cGAS

References

1. One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.