NMDI14

TargetMol
Product Code: TAR-T12235
Supplier: TargetMol
CodeSizePrice
TAR-T12235-1mg1mg£96.00
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TAR-T12235-2mg2mg£106.00
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TAR-T12235-5mg5mg£128.00
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TAR-T12235-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T12235-10mg10mg£173.00
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TAR-T12235-25mg25mg£294.00
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TAR-T12235-50mg50mg£462.00
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TAR-T12235-100mg100mg£646.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).
CAS:
307519-88-6
Formula:
C21H25N3O4S
Molecular Weight:
415.51
Purity:
0.9937
SMILES:
CCOC(=O)c1c(C)c(C)sc1NC(=O)CC1Nc2cc(C)c(C)cc2NC1=O

References

1. Martin L, et al. Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. Cancer Res. 2014 Jun 1;74(11):3104-1 2. Aksit M A , Bowling A D , Evans T A , et al. Decreased mRNA and protein stability of W1282X limits response to modulator therapy[J]. Journal of Cystic Fibrosis, 2019, 18(5).