PLpro inhibitor

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TargetMol
Product Code: TAR-T12502
Supplier: TargetMol
CodeSizePrice
TAR-T12502-1mg1mg£177.00
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TAR-T12502-2mg2mg£226.00
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TAR-T12502-5mg5mg£303.00
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TAR-T12502-1mL1 mL * 10 mM (in DMSO)£365.00
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TAR-T12502-10mg10mg£402.00
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TAR-T12502-25mg25mg£623.00
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TAR-T12502-50mg50mg£857.00
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TAR-T12502-100mg100mg£1,131.00
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TAR-T12502-500mg500mg£2,183.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
CAS:
1093070-14-4
Formula:
C22H22N2O2
Molecular Weight:
346.43
Pathway:
Microbiology/Virology
Purity:
0.9982
SMILES:
C[C@@H](NC(=O)c1cc(NC(C)=O)ccc1C)c1cccc2ccccc12
Target:
SARS-CoV

References

1. Ratia, K., et al., A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A, 2008. 105(42): p. 16119-24. 2. http://www.google.com/patents/WO2010022355A1cl=en