TTNPB

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TargetMol
Product Code: TAR-T1288
Supplier: TargetMol
CodeSizePrice
TAR-T1288-2mg2mg£97.00
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TAR-T1288-5mg5mg£112.00
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TAR-T1288-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T1288-10mg10mg£134.00
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TAR-T1288-25mg25mg£203.00
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TAR-T1288-50mg50mg£330.00
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TAR-T1288-100mg100mg£462.00
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TAR-T1288-500mg500mg£922.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
TTNPB, a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM), respectively.
CAS:
71441-28-6
Formula:
C24H28O2
Molecular Weight:
348.486
Pathway:
Apoptosis; Metabolism; Autophagy
Purity:
0.9884
SMILES:
CC(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Target:
Apoptosis; Retinoid Receptor; Autophagy

References

1. Pignatello MA, et al. Toxicol Appl Pharmacol. 1997, 142(2), 319-327. 2. Pignatello MA, et al. Toxicol Appl Pharmacol. 1999, 159(2), 109-116. 3. Wu K, et al. Breast Cancer Res Treat. 2006, 96(2), 147-157. 4. Louisse J, et al. Toxicol Lett. 2011, 203(1), 1-8. 5. Darro F, et al. Breast Cancer Res Treat. 1998, 51(1), 39-55.