VU 0365114

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TargetMol
Product Code: TAR-T13325
Supplier: TargetMol
CodeSizePrice
TAR-T13325-1mg1mg£101.00
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TAR-T13325-2mg2mg£114.00
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TAR-T13325-5mg5mg£142.00
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TAR-T13325-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T13325-10mg10mg£171.00
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TAR-T13325-25mg25mg£257.00
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TAR-T13325-50mg50mg£385.00
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TAR-T13325-100mg100mg£544.00
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TAR-T13325-500mg500mg£1,099.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).
CAS:
1208222-39-2
Formula:
C22H14F3NO3
Molecular Weight:
397.353
Pathway:
Neuroscience
Purity:
0.98
SMILES:
FC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccccc3)C(=O)C(=O)c2c1
Target:
AChR

References

1. Bridges TM, et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5617-22.