BMX-IN-1

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TargetMol
Product Code: TAR-T14692
Supplier: TargetMol
CodeSizePrice
TAR-T14692-1mg1mg£109.00
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TAR-T14692-2mg2mg£128.00
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TAR-T14692-5mg5mg£182.00
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TAR-T14692-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T14692-10mg10mg£269.00
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TAR-T14692-25mg25mg£405.00
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TAR-T14692-50mg50mg£568.00
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TAR-T14692-100mg100mg£777.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
BMX-IN-1 is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton?s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
CAS:
1431525-23-3
Formula:
C29H24N4O4S
Molecular Weight:
524.6
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cc1ccc(cc1NC(=O)C=C)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1ccc(NS(C)(=O)=O)cc1
Target:
BTK

References

1. Feiyang Liu , et al. Discovery of a Selective Irreversible BMX Inhibitor for Prostate Cancer. ACS Chem. Biol., DOI: 10.1021/cb4000629 1. Feiyang Liu, et al. Discovery of a Selective Irreversible BMX Inhibitor for Prostate Cancer. ACS Chem. Biol.