CDK9-IN-2

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TargetMol
Product Code: TAR-T14918
Supplier: TargetMol
CodeSizePrice
TAR-T14918-1mg1mg£135.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T14918-5mg5mg£229.00
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Quantity:
TAR-T14918-1mL1 mL * 10 mM (in DMSO)£245.00
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Quantity:
TAR-T14918-10mg10mg£308.00
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Quantity:
TAR-T14918-25mg25mg£482.00
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Quantity:
TAR-T14918-50mg50mg£667.00
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Quantity:
TAR-T14918-100mg100mg£914.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
CDK9-IN-2 is a special CDK9 inhibitor extracted from patent WO/2012131594A1 (compound CDKI(8)) and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively.
CAS:
1263369-28-3
Formula:
C23H25ClFN5
Molecular Weight:
425.94
Pathway:
Cell Cycle/Checkpoint;
Purity:
0.98
SMILES:
N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCc2cccc(F)c2)n1
Target:
CDK

References

1. Michel Faure, et al. Pharmacodynamic markers associated with cyclin-dependent kinase inhibitors. From PCT Int. Appl. (2012), WO 2012131594A1.