Centrinone

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TargetMol
Product Code: TAR-T14927
Supplier: TargetMol
CodeSizePrice
TAR-T14927-1mg1mg£115.00
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TAR-T14927-2mg2mg£132.00
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TAR-T14927-5mg5mg£166.00
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TAR-T14927-1mL1 mL * 10 mM (in DMSO)£205.00
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TAR-T14927-10mg10mg£229.00
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TAR-T14927-50mg50mg£438.00
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TAR-T14927-100mg100mg£611.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Centrinone (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).
CAS:
1798871-30-3
Formula:
C26H25F2N7O6S2
Molecular Weight:
633.65
Pathway:
Cell Cycle/Checkpoint; Chromatin/Epigenetic
Purity:
0.9876
SMILES:
COc1c(Nc2cc(C)[nH]n2)nc(Sc2ccc(cc2F)S(=O)(=O)Cc2cccc(c2F)[N+]([O-])=O)nc1N1CCOCC1
Target:
PLK; Aurora Kinase

References

1. Wong YL. et al. Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science. 2015 Jun 5;348(6239):1155-60.