CU-CPT22

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TargetMol
Product Code: TAR-T15020
Supplier: TargetMol
CodeSizePrice
TAR-T15020-1mg1mg£106.00
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TAR-T15020-2mg2mg£122.00
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TAR-T15020-5mg5mg£152.00
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TAR-T15020-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T15020-10mg10mg£208.00
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TAR-T15020-25mg25mg£335.00
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TAR-T15020-50mg50mg£466.00
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TAR-T15020-100mg100mg£647.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 μM). It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41 μM).
CAS:
1416324-85-0
Formula:
C19H22O7
Molecular Weight:
362.378
Pathway:
Immunology/Inflammation
Purity:
0.993
SMILES:
CCCCCCOC(=O)c1cc(O)c(=O)c2c(O)c(O)c(OC)cc2c1
Target:
TLR

References

1. Cheng K, et al. Discovery of small-molecule inhibitors of the TLR1/TLR2 complex. Angew Chem Int Ed Engl. 2012 Dec 3;51(49):12246-9.