Endovion

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TargetMol
Product Code: TAR-T15233
Supplier: TargetMol
CodeSizePrice
TAR-T15233-1mg1mg£98.00
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TAR-T15233-2mg2mg£109.00
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TAR-T15233-5mg5mg£132.00
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TAR-T15233-1mL1 mL * 10 mM (in DMSO)£141.00
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TAR-T15233-10mg10mg£177.00
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Quantity:
TAR-T15233-25mg25mg£282.00
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Quantity:
TAR-T15233-50mg50mg£450.00
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TAR-T15233-100mg100mg£627.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Endovion is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker.
CAS:
265646-85-3
Formula:
C16H9BrF6N6O
Molecular Weight:
495.183
Pathway:
Membrane transporter/Ion channel
Purity:
0.9831
SMILES:
FC(F)(F)c1cc(NC(=O)Nc2ccc(Br)cc2-c2nnn[nH]2)cc(c1)C(F)(F)F
Target:
Chloride channel

References

1. S?rensen BH, et al. Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against CDDP-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation. Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C857-73. 2. Sauter DR, et al. ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC). Pflugers Arch. 2015 Jul;467(7):1495-1508.