inS3-54A18

TargetMol
Product Code: TAR-T15582
Supplier: TargetMol
CodeSizePrice
TAR-T15582-1mg1mg£125.00
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TAR-T15582-2mg2mg£148.00
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TAR-T15582-1mL1 mL * 10 mM (in DMSO)£174.00
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TAR-T15582-5mg5mg£197.00
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TAR-T15582-10mg10mg£277.00
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TAR-T15582-25mg25mg£499.00
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Quantity:
TAR-T15582-50mg50mg£691.00
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TAR-T15582-100mg100mg£938.00
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TAR-T15582-500mg500mg£1,813.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.
CAS:
328998-53-4
Formula:
C23H16ClNO2
Molecular Weight:
373.84
Pathway:
Stem Cells; JAK/STAT signaling
Purity:
0.9954
SMILES:
Oc1ccc(cc1)N1C(=O)C(=C/c2ccc(Cl)cc2)C=C1c1ccccc1
Target:
STAT

References

1. Huang W, et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene. 2016 Feb 11;35(6):783-92