JJKK 048

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TargetMol
Product Code: TAR-T15614
Supplier: TargetMol
CodeSizePrice
TAR-T15614-1mg1mg£95.00
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TAR-T15614-2mg2mg£106.00
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TAR-T15614-5mg5mg£128.00
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TAR-T15614-1mL1 mL * 10 mM (in DMSO)£134.00
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TAR-T15614-10mg10mg£161.00
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TAR-T15614-25mg25mg£269.00
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TAR-T15614-50mg50mg£389.00
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TAR-T15614-100mg100mg£546.00
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TAR-T15614-500mg500mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
JJKK 048 is a potent and selective MAGL inhibitor.
CAS:
1515855-97-6
Formula:
C23H22N4O5
Molecular Weight:
434.452
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C(N1CCC(CC1)C(c1ccc2OCOc2c1)c1ccc2OCOc2c1)n1cncn1
Target:
Lipase

References

1. Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90. 2. Aaltonen N, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048). J Pharmacol Exp Ther. 2016 Oct;359(1):62-72.