Cipargamin

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TargetMol
Product Code: TAR-T16326
Supplier: TargetMol
CodeSizePrice
TAR-T16326-1mg1mg£113.00
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TAR-T16326-2mg2mg£132.00
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TAR-T16326-5mg5mg£185.00
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TAR-T16326-1mL1 mL * 10 mM (in DMSO)£197.00
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TAR-T16326-10mg10mg£254.00
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TAR-T16326-25mg25mg£422.00
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TAR-T16326-50mg50mg£667.00
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TAR-T16326-100mg100mg£1,026.00
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TAR-T16326-200mg200mg£1,340.00
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TAR-T16326-500mg500mg£1,982.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Cipargamin is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum.
CAS:
1193314-23-6
Formula:
C19H14Cl2FN3O
Molecular Weight:
390.24
Pathway:
Microbiology/Virology
Purity:
0.9858
SMILES:
C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21
Target:
Parasite

References

1. Zhou Y, et al. Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivo. Antimicrob Agents Chemother. 2014;58(3):1789-92. 2. van Pelt-Koops JC, et al. The spiroindolone drug candidate NITD609 potently inhibits gametocytogenesis and blocks Plasmodium falciparum transmission to anopheles mosquito vector. Antimicrob Agents Chemother. 2012 Jul;56(7):3544-8. 3. Rottmann M, et al. Spiroindolones, a potent compound class for the treatment of malaria. Science. 2010 Sep 3;329(5996):1175-80.