RU-302

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TargetMol
Product Code: TAR-T16806
Supplier: TargetMol
CodeSizePrice
TAR-T16806-1mg1mg£119.00
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TAR-T16806-2mg2mg£141.00
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TAR-T16806-5mg5mg£189.00
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TAR-T16806-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T16806-10mg10mg£275.00
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TAR-T16806-25mg25mg£436.00
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TAR-T16806-50mg50mg£610.00
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TAR-T16806-100mg100mg£838.00
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TAR-T16806-500mg500mg£1,613.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor growth.
CAS:
1182129-77-6
Formula:
C24H24F3N3O2S
Molecular Weight:
475.53
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9945
SMILES:
Cc1noc(C)c1CSc1ccccc1C(=O)N1CCN(CC1)c1cccc(c1)C(F)(F)F
Target:
TAM Receptor

References

1. Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908.