Tipifarnib (S enantiomer)

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TargetMol
Product Code: TAR-T17102
Supplier: TargetMol
CodeSizePrice
TAR-T17102-1mg1mg£134.00
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TAR-T17102-2mg2mg£163.00
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TAR-T17102-5mg5mg£216.00
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TAR-T17102-1mL1 mL * 10 mM (in DMSO)£227.00
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TAR-T17102-10mg10mg£305.00
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TAR-T17102-25mg25mg£493.00
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TAR-T17102-50mg50mg£680.00
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TAR-T17102-100mg100mg£930.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).
CAS:
192185-71-0
Formula:
C27H22Cl2N4O
Molecular Weight:
489.4
Pathway:
Metabolism
Purity:
0.9905
SMILES:
Cn1cncc1[C@](N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1
Target:
Transferase

References

1. Kraus JM, et al. Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem. 2009 Mar 26;52(6):1639-47.