4E1rcat

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TargetMol
Product Code: TAR-T1742
Supplier: TargetMol
CodeSizePrice
TAR-T1742-2mg2mg£108.00
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TAR-T1742-5mg5mg£125.00
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TAR-T1742-1mL1 mL * 10 mM (in DMSO)£131.00
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TAR-T1742-10mg10mg£145.00
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TAR-T1742-25mg25mg£203.00
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TAR-T1742-50mg50mg£237.00
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TAR-T1742-100mg100mg£367.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.
CAS:
328998-25-0
Formula:
C28H18N2O6
Molecular Weight:
478.46
Pathway:
Autophagy; Apoptosis
Purity:
0.9936
SMILES:
OC(=O)c1ccc(cc1)N1C(=O)C(=C/c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1
Target:
PERK; Autophagy

References

1. Shuda M, et al. Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82.