LY2090314

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TargetMol
Product Code: TAR-T1755
Supplier: TargetMol
CodeSizePrice
TAR-T1755-1mg1mg£103.00
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TAR-T1755-2mg2mg£116.00
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TAR-T1755-5mg5mg£148.00
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TAR-T1755-1mL1 mL * 10 mM (in DMSO)£158.00
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TAR-T1755-10mg10mg£195.00
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TAR-T1755-25mg25mg£294.00
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TAR-T1755-50mg50mg£436.00
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TAR-T1755-100mg100mg£610.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
CAS:
603288-22-8
Formula:
C28H25FN6O3
Molecular Weight:
512.545
Pathway:
PI3K/Akt/mTOR signaling; Stem Cells
Purity:
0.9988
SMILES:
Fc1cc2CN(CCn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23)C(=O)N1CCCCC1
Target:
GSK-3

References

1. Brail LH, et al. J Clin Oncol, 2011, 29, abstr 3030.