PI3K-IN-1

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TargetMol
Product Code: TAR-T1826
Supplier: TargetMol
CodeSizePrice
TAR-T1826-1mg1mg£95.00
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TAR-T1826-2mg2mg£105.00
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TAR-T1826-5mg5mg£125.00
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TAR-T1826-1mL1 mL * 10 mM (in DMSO)£143.00
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TAR-T1826-10mg10mg£164.00
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TAR-T1826-25mg25mg£256.00
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TAR-T1826-50mg50mg£334.00
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TAR-T1826-100mg100mg£497.00
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TAR-T1826-500mg500mg£1,018.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Voxtalisib (SAR245409, XL765)Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.
CAS:
1349796-36-6
Formula:
C31H29N5O6S
Molecular Weight:
599.66
Pathway:
PI3K/Akt/mTOR signaling; DNA Damage/DNA Repair
Purity:
0.98
SMILES:
COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)c3ccc(C)c(OC)c3)cc2)cc(OC)c1
Target:
DNA-PK; PI3K

References

1. Garcia-Echeverria C, et al. Oncogene, 2008, 27(41), 5511-5526. 2. Mirzoeva OK, et al. J Mol Med, 2011, 89(9), 877-889. 3. Prasad G, et al. Neuro Oncol, 2011, 13(4), 384-392.