TMP269

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TargetMol
Product Code: TAR-T1857
Supplier: TargetMol
CodeSizePrice
TAR-T1857-2mg2mg£124.00
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TAR-T1857-5mg5mg£148.00
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TAR-T1857-1mL1 mL * 10 mM (in DMSO)£170.00
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TAR-T1857-10mg10mg£202.00
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TAR-T1857-25mg25mg£291.00
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TAR-T1857-50mg50mg£467.00
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TAR-T1857-100mg100mg£550.00
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TAR-T1857-200mg200mg£760.00
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TAR-T1857-500mg500mg£1,107.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
TMP269 is an effective, specific class IIa HDAC inhibitor for HDAC4 (IC50: 157 nM), HDAC5 (IC50: 97 nM), HDAC7 (IC50: 43 nM), and HDAC9 (IC50: 23 nM), respectively.
CAS:
1314890-29-3
Formula:
C25H21F3N4O3S
Molecular Weight:
514.52
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9906
SMILES:
FC(F)(F)c1nc(no1)-c1cccc(c1)C(=O)NCC1(CCOCC1)c1nc(cs1)-c1ccccc1
Target:
HDAC

References

1. Lobera M, et al. Nat Chem Biol. 2013, 9(5), 319-325. 2. Sinnett-Smith J, et al. Am J Physiol Cell Physiol. 2014, 306(10), C961-971.