Inauhzin

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TargetMol
Product Code: TAR-T1887
Supplier: TargetMol
CodeSizePrice
TAR-T1887-1mg1mg£100.00
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TAR-T1887-2mg2mg£111.00
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TAR-T1887-5mg5mg£144.00
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TAR-T1887-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T1887-10mg10mg£160.00
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TAR-T1887-25mg25mg£262.00
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TAR-T1887-50mg50mg£398.00
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TAR-T1887-100mg100mg£540.00
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TAR-T1887-500mg500mg£1,091.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
CAS:
309271-94-1
Formula:
C25H19N5OS2
Molecular Weight:
469.58
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.9936
SMILES:
CCC(Sc1nnc2c(n1)[nH]c1ccccc21)C(=O)N1c2ccccc2Sc2ccccc12
Target:
Sirtuin

References

1. Zhang Q, et al. EMBO Mol Med. 2012 Apr; 4(4): 298-31