CHS-828

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TargetMol
Product Code: TAR-T1998
Supplier: TargetMol
CodeSizePrice
TAR-T1998-2mg2mg£95.00
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TAR-T1998-5mg5mg£111.00
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TAR-T1998-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T1998-10mg10mg£134.00
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TAR-T1998-25mg25mg£203.00
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TAR-T1998-50mg50mg£283.00
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TAR-T1998-100mg100mg£411.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
GMX1778(CHS-828), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).
CAS:
200484-11-3
Formula:
C19H22ClN5O
Molecular Weight:
371.87
Pathway:
Metabolism; Apoptosis
Purity:
0.9976
SMILES:
Clc1ccc(OCCCCCCNC(NC#N)=Nc2ccncc2)cc1
Target:
Apoptosis; NAMPT

References

1. Watson M, et al. Mol Cell Biol. 2009, 29(21), 5872-5888. 2. Hansen CM, et al. Anticancer Res. 2000, 20(6B), 4211-4220. 3. Olsen LS, et al. Int J Cancer. 2004, 111(2), 198-205. 4. Johanson V, et al. Neuroendocrinology. 2005, 82(3-4), 171-176.