Tiplaxtinin

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TargetMol
Product Code: TAR-T2030
Supplier: TargetMol
CodeSizePrice
TAR-T2030-2mg2mg£100.00
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TAR-T2030-5mg5mg£118.00
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TAR-T2030-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T2030-10mg10mg£140.00
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TAR-T2030-25mg25mg£196.00
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TAR-T2030-50mg50mg£290.00
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TAR-T2030-100mg100mg£503.00
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TAR-T2030-500mg500mg£994.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Tiplaxtinin(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.
CAS:
393105-53-8
Formula:
C24H16F3NO4
Molecular Weight:
439.39
Pathway:
Metabolism; Apoptosis
Purity:
0.9949
SMILES:
OC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1
Target:
PAI-1; Apoptosis

References

1. Elokdah H, et al. J Med Chem. 2004, 47(14), 3491-3494. 2. Weisberg AD, et al. Arterioscler Thromb Vasc Biol. 2005, 25(2), 365-371. 3. Krause MP, et al. Diabetes. 2011, 60(7), 1964-1972. 4. Gomes-Giacoia E, et al. Mol Cancer Ther. 2013, 12(12), 2697-2708.