TH588

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TargetMol
Product Code: TAR-T2037
Supplier: TargetMol
CodeSizePrice
TAR-T2037-2mg2mg£99.00
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TAR-T2037-5mg5mg£116.00
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Quantity:
TAR-T2037-1mL1 mL * 10 mM (in DMSO)£121.00
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Quantity:
TAR-T2037-10mg10mg£137.00
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TAR-T2037-25mg25mg£173.00
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TAR-T2037-50mg50mg£246.00
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Quantity:
TAR-T2037-100mg100mg£400.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.
CAS:
1609960-31-7
Formula:
C13H12Cl2N4
Molecular Weight:
295.17
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9957
SMILES:
Nc1nc(NC2CC2)cc(n1)-c1cccc(Cl)c1Cl
Target:
DNA/RNA Synthesis; MTH1

References

1. Gad H, et al. Nature. 2014, 508(7495), 215-221.