TH287

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TargetMol
Product Code: TAR-T2069
Supplier: TargetMol
CodeSizePrice
TAR-T2069-2mg2mg£103.00
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TAR-T2069-5mg5mg£124.00
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TAR-T2069-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T2069-10mg10mg£148.00
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TAR-T2069-25mg25mg£230.00
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TAR-T2069-50mg50mg£381.00
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TAR-T2069-100mg100mg£531.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.
CAS:
1609960-30-6
Formula:
C11H10Cl2N4
Molecular Weight:
269.13
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.99
SMILES:
CNc1cc(nc(N)n1)-c1cccc(Cl)c1Cl
Target:
DNA/RNA Synthesis; MTH1

References

1. Gad H, et al. Nature. 2014, 508(7495), 215-221. 2. Saleh A, et al. J Pharm Biomed Anal. 2015, 104, 1-11.