Agerafenib

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TargetMol
Product Code: TAR-T2070
Supplier: TargetMol
CodeSizePrice
TAR-T2070-1mg1mg£101.00
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TAR-T2070-2mg2mg£114.00
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TAR-T2070-5mg5mg£142.00
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TAR-T2070-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T2070-10mg10mg£177.00
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Quantity:
TAR-T2070-25mg25mg£266.00
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Quantity:
TAR-T2070-50mg50mg£389.00
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TAR-T2070-100mg100mg£547.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
CEP-32496 is a highly potent inhibitor of BRAF.
CAS:
1188910-76-0
Formula:
C24H22F3N5O5
Molecular Weight:
517.465
Pathway:
Apoptosis; Angiogenesis; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
Purity:
0.9923
SMILES:
COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1OC
Target:
Raf; c-RET; Bcr-Abl; PDGFR; Src; c-Kit

References

1. Rowbottom MW, et al. J Med Chem, 2012, 55(3), 1082-1105. 2. James J, et al. Mol Cancer Ther, 2012, 11(4), 930-941.