PiB

TargetMol
Product Code: TAR-T21000
Supplier: TargetMol
CodeSizePrice
TAR-T21000-1mg1mg£100.00
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TAR-T21000-2mg2mg£111.00
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TAR-T21000-5mg5mg£128.00
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Quantity:
TAR-T21000-1mL1 mL * 10 mM (in DMSO)£134.00
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Quantity:
TAR-T21000-10mg10mg£149.00
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Quantity:
TAR-T21000-25mg25mg£217.00
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Quantity:
TAR-T21000-50mg50mg£292.00
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TAR-T21000-100mg100mg£402.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
PiB is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.
CAS:
566169-93-5
Formula:
C14H12N2OS
Molecular Weight:
256.32
Purity:
0.9702
SMILES:
CNc1ccc(cc1)-c1nc2ccc(O)cc2s1

References

1. Bourgeat P, et al. Implementing the centiloid transformation for (11)C-PiB and ?-amyloid (18)F-PET tracers using CapAIBL. Neuroimage. 2018 Dec;183:387-393. 2. Yan Q, Nho K, Del-Aguila JL, Wang X, Risacher SL, Fan KH, Snitz BE, Aizenstein HJ, Mathis CA, Lopez OL, Demirci FY, Feingold E, Klunk WE, Saykin AJ; Alzheimer?s Disease Neuroimaging Initiative (ADNI), Cruchaga C, Kamboh MI. Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging. Mol Psychiatry. 2018 Oct 25. doi: 10.1038/s41380-018-0246-7. [Epub ahead of print] PubMed PMID: 30361487. 3. Joie R, Ayakta N, Seeley WW, Borys E, Boxer AL, DeCarli C, Dor? V, Grinberg LT, Huang E, Hwang JH, Ikonomovic MD, Jack C Jr, Jagust WJ, Jin LW, Klunk WE, Kofler J, Lesman-Segev OH, Lockhart SN, Lowe VJ, Masters CL, Mathis CA, McLean CL, Miller BL, Mungas D, O'Neil JP, Olichney JM, Parisi JE, Petersen RC, Rosen HJ, Rowe CC, Spina S, Vemuri P, Villemagne VL, Murray ME, Rabinovici GD. Multisite study of the relationships between antemortem [(11)C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology. Alzheimers Dement. 2018 Oct 19. pii: S1552-5260(18)33523-4. doi: 10.1016/j.jalz.2018.09.001. [Epub ahead of print] PubMed PMID: 30347188. 4. Yokoi T, Watanabe H, Yamaguchi H, Bagarinao E, Masuda M, Imai K, Ogura A, Ohdake R, Kawabata K, Hara K, Riku Y, Ishigaki S, Katsuno M, Miyao S, Kato K, Naganawa S, Harada R, Okamura N, Yanai K, Yoshida M, Sobue G. Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer's Disease: A PET (THK5351, PiB) and Resting fMRI Study. Front Aging Neurosci. 2018 Oct 5;10:304. doi: 10.3389/fnagi.2018.00304. eCollection 2018. PubMed PMID: 30344488; PubMed Central PMCID: PMC6182068.