Ispinesib

TargetMol
Product Code: TAR-T2103
Supplier: TargetMol
CodeSizePrice
TAR-T2103-1mg1mg£97.00
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TAR-T2103-2mg2mg£107.00
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TAR-T2103-5mg5mg£128.00
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TAR-T2103-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T2103-10mg10mg£168.00
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TAR-T2103-25mg25mg£249.00
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TAR-T2103-50mg50mg£356.00
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TAR-T2103-100mg100mg£542.00
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TAR-T2103-500mg500mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Ispinesib, a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
CAS:
336113-53-2
Formula:
C30H33ClN4O2
Molecular Weight:
517.07
Pathway:
Apoptosis; Cytoskeletal Signaling; Cell Cycle/Checkpoint
Purity:
0.9957
SMILES:
CC(C)[C@@H](N(CCCN)C(=O)c1ccc(C)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1
Target:
Apoptosis; Kinesin; KSP

References

1. Lad L, et al. Biochemistry, 2008, 47(11), 3576-3585. 2. Johnson RK, et al. Proc Am Assoc Cancer Res, 2002, 43, 269. 3. Davis DA, et al. BMC Cancer, 2006, 6, 22. 4. Purcell JW, et al. Clin Cancer Res, 2010, 16(2), 566-576.