SD-208

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TargetMol
Product Code: TAR-T2109
Supplier: TargetMol
CodeSizePrice
TAR-T2109-1mg1mg£98.00
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TAR-T2109-2mg2mg£108.00
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TAR-T2109-5mg5mg£129.00
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TAR-T2109-10mg10mg£153.00
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TAR-T2109-1mL1 mL * 10 mM (in DMSO)£161.00
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TAR-T2109-25mg25mg£244.00
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TAR-T2109-50mg50mg£333.00
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TAR-T2109-100mg100mg£481.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SD-208, a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.
CAS:
627536-09-8
Formula:
C17H10ClFN6
Molecular Weight:
352.76
Pathway:
Stem Cells
Purity:
0.98
SMILES:
Fc1ccc(Cl)cc1-c1nc(Nc2ccncc2)c2nccnc2n1
Target:
TGF-beta/Smad

References

1. Uhl M, et al. Cancer Res. 2004, 64(21), 7954-7961. 2. Ge R, et al. Clin Cancer Res. 2006, 12(14 Pt 1), 4315-4330. 3. Sun Y, et al. J Heart Lung Transplant. 2014, 33(6), 654-661.