AEE788

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TargetMol
Product Code: TAR-T2116
Supplier: TargetMol
CodeSizePrice
TAR-T2116-2mg2mg£102.00
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TAR-T2116-5mg5mg£122.00
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TAR-T2116-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T2116-10mg10mg£155.00
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TAR-T2116-25mg25mg£230.00
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TAR-T2116-50mg50mg£346.00
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TAR-T2116-100mg100mg£485.00
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TAR-T2116-500mg500mg£1,002.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.
CAS:
497839-62-0
Formula:
C27H32N6
Molecular Weight:
440.595
Pathway:
JAK/STAT signaling; Apoptosis; Angiogenesis; Tyrosine Kinase/Adaptors; Cytoskeletal Signaling
Purity:
0.98
SMILES:
CCN1CCN(Cc2ccc(cc2)-c2cc3c(N[C@H](C)c4ccccc4)ncnc3[nH]2)CC1
Target:
Apoptosis; EGFR; c-Fms; FLT; Bcr-Abl

References

1. Traxler P, et al. Cancer Res, 2004, 64(14), 4931-4941. 2. Park YW, et al. Clin Cancer Res, 2005, 11(5), 1963-1973. 3. Yokoi K, et al. Cancer Res, 2005, 65(9), 3716-3725. 4. Meco D, et al. Transl Oncol, 2010, 3(5), 326-335. 5. Yu C, et al. Clin Cancer Res, 2007, 13(4), 1140-1148.