SBI-0206965

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TargetMol
Product Code: TAR-T2128
Supplier: TargetMol
CodeSizePrice
TAR-T2128-2mg2mg£101.00
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TAR-T2128-5mg5mg£119.00
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TAR-T2128-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T2128-10mg10mg£152.00
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TAR-T2128-25mg25mg£213.00
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TAR-T2128-50mg50mg£302.00
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TAR-T2128-100mg100mg£430.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
CAS:
1884220-36-3
Formula:
C21H21BrN4O5
Molecular Weight:
489.326
Pathway:
Apoptosis; Autophagy
Purity:
0.9886
SMILES:
CNC(=O)c1ccccc1Oc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Br
Target:
Apoptosis; Autophagy

References

1. Elokdah H, et al. J Med Chem. 2004, 47(14), 3491-3494. 3. Zhang H, Cui Z, Cheng D, et al. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis[J]. Autophagy . 2020